{"id":173,"date":"2026-10-13T10:36:00","date_gmt":"2026-10-13T02:36:00","guid":{"rendered":"http:\/\/duanmu.9ykeji.com\/index.php\/products\/sedanling-pt\/"},"modified":"2026-10-15T15:37:41","modified_gmt":"2026-10-15T07:37:41","slug":"sedanling-pt","status":"publish","type":"product","link":"http:\/\/duanmu.9ykeji.com\/index.php\/pt\/products\/sedanling-pt\/","title":{"rendered":"SDL (dilaurato de sacarose + laurato de sacarose)"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Ingredientes clareadores convencionais interrompem as vias de forma\u00e7\u00e3o da melanina atuando em cada n\u00f3 da melanog\u00eanese. A Sepiwhite MSH adota um mecanismo distinto. Ao contr\u00e1rio dos princ\u00edpios tradicionais de desvanecimento, inibe a prote\u00edna HMGB1 para suprimir a forma\u00e7\u00e3o de dendrito de melan\u00f3citos e bloquear a transfer\u00eancia de melanina para os queratin\u00f3citos. Ele restringe a forma\u00e7\u00e3o de melanina na fonte e reduz a forma\u00e7\u00e3o de manchas e marcas de acne<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Informa\u00e7\u00f5es sobre a composi\u00e7\u00e3o<\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>Tipo de componente<\/th><th>INCI<\/th><th>CAS<\/th><th>EC<\/th><\/tr><\/thead><tbody><tr><td>Componentes<\/td><td>SUCROSE DILAURATE<\/td><td>25915-57-5 <\/td><td>247-345-5 <\/td><\/tr><tr><td>Componentes<\/td><td>SUCROSE LAURATE<\/td><td>25339-99-5 \/ 37266-93-6<\/td><td>246-873-3 \/ 253-432-9<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">Literatura e patentes<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Apoiado por trabalhos de pesquisa publicados no * Jornal da Academia Europeia de Dermatologia e Venereologia (JEADV)*.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Mecanismo de a\u00e7\u00e3o<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">1. Inibi\u00e7\u00e3o da libera\u00e7\u00e3o de HMGB1: SDL reduz a libera\u00e7\u00e3o da prote\u00edna HMGB1 celular em uma maneira dose-dependente.<br>2. Inibi\u00e7\u00e3o do crescimento do dendrite do melanocyte: O downregulation de HMGB1 suprime o comprimento e a ramifica\u00e7\u00e3o de dendrites do melanocyte.<br>3. Bloqueio do transporte do pigmento: A transfer\u00eancia de melanosomes aos keratinocytes \u00e9 obstru\u00edda, reduzindo o dep\u00f3sito do pigmento e a forma\u00e7\u00e3o do ponto.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Dados experimentais<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">1. Teste de inibi\u00e7\u00e3o da libera\u00e7\u00e3o HMGB1: A libera\u00e7\u00e3o de HMGB1 diminui com o aumento da concentra\u00e7\u00e3o de SDL de maneira dependente da dose.<br>2. Teste da \u00e1rea do ponto humano: Para a formula\u00e7\u00e3o com SDL 1%, a redu\u00e7\u00e3o significativa na fra\u00e7\u00e3o da \u00e1rea do ponto \u00e9 observada na semana 4, semana 6 e semana 8 comparada com o grupo de controle.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>N\u00e3o inibe diretamente a tirosinase; visa a prote\u00edna HMGB1, inibe a forma\u00e7\u00e3o de dendrito de melan\u00f3citos e bloqueia o transporte do melanossoma para os queratin\u00f3citos; o efeito inibit\u00f3rio \u00e9 revers\u00edvel com boa seguran\u00e7a celular<\/p>\n","protected":false},"featured_media":422,"menu_order":0,"template":"","meta":[],"product_cat":[102],"product_tag":[],"class_list":["post-173","product","type-product","status-publish","has-post-thumbnail","hentry","product_cat-meibai-danban-pt"],"_links":{"self":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product\/173","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/media\/422"}],"wp:attachment":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/media?parent=173"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=173"},{"taxonomy":"product_tag","embeddable":true,"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=173"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}