{"id":195,"date":"2026-10-13T10:37:00","date_gmt":"2026-10-13T02:37:00","guid":{"rendered":"http:\/\/duanmu.9ykeji.com\/index.php\/products\/yufu-silicon-en\/"},"modified":"2026-10-15T15:37:44","modified_gmt":"2026-10-15T07:37:44","slug":"yufu-silicon-en","status":"publish","type":"product","link":"http:\/\/duanmu.9ykeji.com\/index.php\/en\/products\/yufu-silicon-en\/","title":{"rendered":"SkinHeal Silane"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Silanediol salicylate is based on salicylic acid, a classic skincare ingredient. Through sophisticated organosilicon structural modification, it achieves an optimal balance between efficacy and mildness. It fully inherits the core advantage of salicylic acid for soothing and anti-inflammation, and overcomes the drawbacks of conventional salicylic acid: high irritation and poor stability.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Composition Information<\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>Component Type<\/th><th>INCI<\/th><th>CAS<\/th><th>EC<\/th><\/tr><\/thead><tbody><tr><td>Components<\/td><td>SILANEDIOL SALICYLATE<\/td><td><\/td><td><\/td><\/tr><tr><td>Components<\/td><td>METHYLPROPANEDIOL<\/td><td>2163-42-0<\/td><td>412-350-5<\/td><\/tr><tr><td>Components<\/td><td>AQUA<\/td><td>7732-18-5<\/td><td>231-791-2<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">Mechanism of Action<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">1. Soothing &amp; anti-sensitivity pathway: Inhibit the activation of NF\u2011\u03baB signaling pathway; downregulate inflammatory factors IL\u20116, TNF\u2011\u03b1 and IL\u20111\u03b2, suppress the expression of iNOS and COX\u20112, reduce NO production, relieve skin inflammatory response and alleviate redness and burning sensation.<br>2. Dermal repair pathway: Reactive silicon participates in skin structure construction, promotes fibroblast proliferation, boosts synthesis of type \u2160 collagen and elastin, optimizes the arrangement of dermal collagen fibers and strengthens skin structure.<br>3. Photoprotective pathway: Precondition epidermal cells to mitigate UVB-induced cell damage and reduce photodamage.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Experimental Data<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">1. Anti-inflammation test on RAW264.7 cells (15 \u03bcg\/mL SkinHeal Silane): IL\u20116 inhibition 75%, TNF\u2011\u03b1 inhibition 46.7%, IL\u20111\u03b2 inhibition 92.9%; NO production inhibition 35.7%; NF\u2011\u03baB protein inhibition 98.5%.<br>2. Fibroblast proliferation test (2% SkinHeal Silane): It promotes fibroblast proliferation with a promotion rate of 42%.<br>3. Human dermal explant test (2% SkinHeal Silane): Type \u2160 collagen fibers become more uniformly and densely arranged, and elastin content increases.<br>4. UVB photodamage protection test: Pre-treatment with 2% SkinHeal Silane protects epidermal structure and alleviates cell damage induced by UVB irradiation.<br>5. Human redness test (2% SkinHeal Silane repair cream): Redness improvement is observed at 24 h, continuous relief at 36 h, and obvious redness repair after 7 days.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Salicylic acid derivative; retains the anti\u2011inflammatory benefits of salicylic acid and overcomes the drawbacks of high irritation and poor stability of conventional salicylic acid; possesses dual capacities of anti\u2011inflammatory soothing and dermal repair; the reactive silicon offers good skin affinity and assists active ingredients to penetrate into the skin<\/p>\n","protected":false},"featured_media":400,"menu_order":0,"template":"","meta":[],"product_cat":[105],"product_tag":[],"class_list":["post-195","product","type-product","status-publish","has-post-thumbnail","hentry","product_cat-kangyan-shumin-en"],"_links":{"self":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product\/195","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/media\/400"}],"wp:attachment":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/media?parent=195"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=195"},{"taxonomy":"product_tag","embeddable":true,"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=195"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}