{"id":216,"date":"2026-10-13T10:37:55","date_gmt":"2026-10-13T02:37:55","guid":{"rendered":"http:\/\/duanmu.9ykeji.com\/index.php\/products\/stx-like-peptide-en\/"},"modified":"2026-10-15T15:37:46","modified_gmt":"2026-10-15T07:37:46","slug":"stx-like-peptide-en","status":"publish","type":"product","link":"http:\/\/duanmu.9ykeji.com\/index.php\/en\/products\/stx-like-peptide-en\/","title":{"rendered":"SaxiMimic Peptide"},"content":{"rendered":"\n

Wrinkle-Relax Peptide mimics saxitoxin, one of the most toxic known marine biotoxins and a major toxin responsible for paralytic shellfish poisoning. It binds to the toxin receptor on Na\u207a channel proteins of neurons and sarcolemma, blocking Na\u207a channels and preventing sodium influx. This disturbs neuromuscular transmission and induces relaxation and paralysis of voluntary muscles, thereby delivering instant wrinkle reduction<\/p>\n\n\n\n

Composition Information<\/h3>\n\n\n\n
Component Type<\/th>INCI<\/th>CAS<\/th>EC<\/th><\/tr><\/thead>
Components<\/td>ARGININE\/LYSINE POLYPEPTIDE<\/td>31014-78-5<\/td><\/td><\/tr>
Components<\/td>ERGOTHIONEINE<\/td>497-30-3<\/td>207-843-5<\/td><\/tr>
Components<\/td>NICOTINAMIDE ADENINE DINUCLEOTIDE<\/td>53-84-9<\/td>200-184-4<\/td><\/tr>
Components<\/td>ZANTHOXYLUM ALATUM EXTRACT<\/td><\/td><\/td><\/tr>
Components<\/td>CENTELLA ASIATICA EXTRACT<\/td>84696-21-9<\/td>283-640-5<\/td><\/tr>
Components<\/td>BUTYLENE GLYCOL<\/td>107-88-0 (i), 6290-03-5 (ii)<\/td>203-529-7 (i), 228-532-0 (ii)<\/td><\/tr>
Components<\/td>HYDROGENATED LECITHIN<\/td>92128-87-5 <\/td>295-786-7<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Mechanism of Action<\/h3>\n\n\n\n

1. Dynamic wrinkle soothing pathway: Saxitoxin-like polypeptide binds to Na\u207a channel receptors on neurons and sarcolemma, blocks Na\u207a influx, interferes with neuromuscular signal transmission, relaxes expression-related muscle tension and improves dynamic expression lines.
2. Mitochondrial anti-aging pathway (ergothioneine + NAD\u207a): Ergothioneine enters cells via OCTN\u20111 transporter and scavenges intracellular and extracellular free radicals. It enhances cGPDH activity to facilitate NAD\u207a production. NAD\u207a activates Sirt1 deacetylase, regulates mitophagy, assists DNA repair, stabilizes telomeres, maintains mitochondrial homeostasis and delays cellular senescence.
3. Soothing pathway (Zanthoxylum armatum extract): Reduce the production of inflammatory factors, scavenge free radicals and mitigate inflammatory stress damage of skin.
4. Barrier repair pathway (centella asiatica extract): Promote migration and proliferation of keratinocytes and fibroblasts to support epidermal repair; downregulate MMP\u20111 expression, slow telomere shortening of fibroblasts and boost collagen synthesis.
5. Matrix homeostasis pathway: Upregulate SOD2 and SIRT3 expression to preserve mitochondrial function; raise hydroxyproline level and stimulate collagen production.<\/p>\n\n\n\n

Experimental Data<\/h3>\n\n\n\n

1. Human facial wrinkle test (3% Serum): After 30 minutes, the quantity and severity of facial wrinkles decrease significantly; the count and severity of crow\u2019s feet are markedly improved.
2. Collagen synthesis test: At sample concentration of 20 \u03bcg\/mL, hydroxyproline (collagen marker) content increases by 106%.
3. Cell scratch migration test: At 250 \u03bcM, fibroblast wound healing rate rises by approx. 20%; at 500 \u03bcM, keratinocyte wound healing rate rises by approx. 48.6%.
4. Mitochondrial protein expression test: At 10 \u03bcM sample, SOD2 expression increases by approx. 40% and SIRT3 expression increases by approx. 75%.
5. Antioxidant test: At 5 mg\/mL, DPPH scavenging rate reaches 91% and ABTS\u207a scavenging rate reaches 95%.<\/p>\n","protected":false},"excerpt":{"rendered":"

Multi-dimensional anti-wrinkle blended raw material; mimics saxitoxin action, blocks sodium channels to inhibit electrical signal transmission for instant muscle soothing and wrinkle reduction; also delivers mitochondrial anti-aging, antioxidant activity, anti-inflammation, collagen synthesis promotion and cell migration repair; covers three wrinkle-generation dimensions: nerve, mitochondria and inflammation<\/p>\n","protected":false},"featured_media":407,"menu_order":0,"template":"","meta":[],"product_cat":[115],"product_tag":[],"class_list":["post-216","product","type-product","status-publish","has-post-thumbnail","hentry","product_cat-kangshuai-niling-en"],"_links":{"self":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product\/216","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/media\/407"}],"wp:attachment":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/media?parent=216"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=216"},{"taxonomy":"product_tag","embeddable":true,"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=216"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}