{"id":219,"date":"2026-10-13T10:38:02","date_gmt":"2026-10-13T02:38:02","guid":{"rendered":"http:\/\/duanmu.9ykeji.com\/index.php\/products\/dixiancao-pe-en\/"},"modified":"2026-10-15T15:37:47","modified_gmt":"2026-10-15T07:37:47","slug":"dixiancao-pe-en","status":"publish","type":"product","link":"http:\/\/duanmu.9ykeji.com\/index.php\/en\/products\/dixiancao-pe-en\/","title":{"rendered":"ReedSap Extract"},"content":{"rendered":"\n

PE acts on estrogen receptors (ER) with dual regulatory characteristics. It can bind to ER and exert phytoestrogen-like activity under low estrogen conditions. When estrogen concentration is high, PE competitively occupies ER binding sites and weakens the binding of endogenous estrogen to ER, showing estrogen antagonistic properties. For this reason, PE is categorized as a selective estrogen receptor modulator (SERM) in academic research. It is gradually being applied in cosmetic formulations for skin care<\/p>\n\n\n\n

Composition Information<\/h3>\n\n\n\n
Component Type<\/th>INCI<\/th>CAS<\/th>EC<\/th><\/tr><\/thead>
Components<\/td>DIOSCOREA MEXICANA ROOT EXTRACT<\/td><\/td><\/td><\/tr>
Components<\/td>PUERARIA LOBATA EXTRACT<\/td><\/td><\/td><\/tr>
Components<\/td>LINUM USITATISSIMUM (LINSEED) SEED EXTRACT<\/td>8001-26-1<\/td>232-278-6<\/td><\/tr>
Components<\/td>CYCLODEXTRIN<\/td>7585-39-9 \/ 12619-70-4<\/td>231-493-2<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Mechanism of Action<\/h3>\n\n\n\n

1. ER receptor bidirectional regulation pathway: Acts as a selective estrogen receptor modulator. When estrogen level is low, it binds to ER receptors and exerts estrogen-like activity; when estrogen level is high, it competitively occupies ER\u03b1 and ER\u03b2 receptors to block the binding of endogenous potent estrogen. It upregulates the expression of ER\u03b1, ER\u03b2 and GPR30 receptors.
2. ECM protection pathway: Downregulate MMP\u201113 matrix metalloproteinase to reduce matrix degradation; upregulate aggrecan (ACAN) and type \u2161 collagen (COL\u2011\u2161) to maintain elastic tissue structure.
3. Antioxidant pathway: Scavenge DPPH free radicals, enhance SOD antioxidant enzyme activity and reduce oxidative stress damage.<\/p>\n\n\n\n

Experimental Data<\/h3>\n\n\n\n

1. In-vitro antioxidant test: 1% PE achieves 67% DPPH radical scavenging rate and 75% elevation of SOD activity.
2. Tumor spheroid 3D inhibition test: At concentration above 148 \u03bcg\/mL, nearly all MDA-MB231 spheroid cells are inactivated.
3. Human in-vivo observation: With long-term application, neck and hand wrinkles are improved visually and neck skin becomes firmer.<\/p>\n","protected":false},"excerpt":{"rendered":"

Plant-derived dual-regulating anti-aging raw material, a selective estrogen receptor modulator; it enables dual regulation of estrogen receptors, with matrix degradation inhibition and antioxidant activity<\/p>\n","protected":false},"featured_media":408,"menu_order":0,"template":"","meta":[],"product_cat":[115],"product_tag":[],"class_list":["post-219","product","type-product","status-publish","has-post-thumbnail","hentry","product_cat-kangshuai-niling-en"],"_links":{"self":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product\/219","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/media\/408"}],"wp:attachment":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/media?parent=219"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=219"},{"taxonomy":"product_tag","embeddable":true,"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=219"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}