{"id":228,"date":"2026-10-13T10:38:25","date_gmt":"2026-10-13T02:38:25","guid":{"rendered":"http:\/\/duanmu.9ykeji.com\/index.php\/products\/doumating-plus-en\/"},"modified":"2026-10-15T15:37:48","modified_gmt":"2026-10-15T07:37:48","slug":"doumating-plus-en","status":"publish","type":"product","link":"http:\/\/duanmu.9ykeji.com\/index.php\/en\/products\/doumating-plus-en\/","title":{"rendered":"Acne&Mite Anti Plus"},"content":{"rendered":"\n

DMT is an active ingredient extracted from multiple precious herbal materials. It effectively inhibits *Cutibacterium acnes* and mites, and also shows good inhibitory activity against *Candida albicans*, *Staphylococcus aureus* and other microorganisms. At an addition level of 2%, it achieves 100% mite inhibition rate within 24 h under test conditions<\/p>\n\n\n\n

Composition Information<\/h3>\n\n\n\n
Component Type<\/th>INCI<\/th>CAS<\/th>EC<\/th><\/tr><\/thead>
Components<\/td>ANDROGRAPHIS PANICULATA EXTRACT<\/td>90244-84-1<\/td>290-788-4<\/td><\/tr>
Components<\/td>SOPHORA ANGUSTIFOLIA ROOT EXTRACT<\/td>164288-54-4<\/td><\/td><\/tr>
Components<\/td>EUCALYPTUS GLOBULUS EXTRACT<\/td>90063-50-6<\/td>290-008-2<\/td><\/tr>
Components<\/td>SYRINGA VULGARIS EXTRACT<\/td><\/td><\/td><\/tr>
Components<\/td>BUTYLENE GLYCOL<\/td>107-88-0 (i), 6290-03-5 (ii)<\/td>203-529-7 (i), 228-532-0 (ii)<\/td><\/tr>
Components<\/td>DIPROPYLENE GLYCOL<\/td>110-98-5 \/ 25265-71-8<\/td>203-821-4 \/ 246-770-3<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Mechanism of Action<\/h3>\n\n\n\n

1. Demodex regulation pathway: Act on cell membrane structure of Demodex, reduce skin Demodex load and relieve redness and skin bumps associated with Demodex.
2. Microbiome balancing pathway: Affect cell structure of *Cutibacterium acnes* and *Malassezia*; inhibit microbial biofilm formation, reduce proliferation of harmful microorganisms in hair follicles and improve inflammatory skin bumps.
3. Sebum regulation pathway: Inhibit type \u2161 5\u03b1-reductase activity, reduce conversion of testosterone into dihydrotestosterone (DHT), lower excessive sebum secretion, improve oily skin and mitigate the trigger of pore clogging.
4. Soothing pathway: Downregulate expression of inflammatory mediators IL\u20111\u03b2, IL\u20116, TNF\u2011\u03b1 and PGE\u2082, relieve skin inflammatory stress induced by UVB and lipopolysaccharide, and alleviate red papules.
5. Antioxidant pathway: Scavenge UVB-induced cellular ROS, reduce oxidative stress damage and ease secondary oxidative damage caused by blemishes.
6. Barrier repair pathway: Increase ceramide content in stratum corneum, reduce transepidermal water loss (TEWL), strengthen skin water retention and repair damaged epidermal barrier of blemish-prone skin.<\/p>\n\n\n\n

Experimental Data<\/h3>\n\n\n\n

1. In-vitro mite-killing test: 2% DMT extract achieves total mite mortality within 10 h with 100% mite reduction at 48 h. 2% DMT cream delivers 100% Demodex mortality in 1 h. For human subjects, average Demodex reduction rate reaches 83.27%, and the best reduction for folliculitis samples hits 86.36%.
2. Bacterial biofilm inhibition test: 1000 mg\/L DMT achieves 96.3% inhibition against Staphylococcus aureus biofilm.
3. 5\u03b1-reductase inhibition test: 2% DMT exhibits 95% inhibitory activity against type II 5\u03b1-reductase and reduces DHT production.
4. Cellular anti-inflammation test: At 6 \u03bcg\/mL DMT, IL\u20111\u03b2 mRNA expression drops by 52.9% and IL\u20116 mRNA by 44.4%. At 60 \u03bcg\/mL, IL\u20116 is reduced by approx. 67.11% and TNF\u2011\u03b1 by approx. 56.49%. It suppresses PGE\u2082 production in a dose-dependent manner with maximum inhibition of 75%.
5. Antioxidant ROS scavenging test: 6 \u03bcg\/mL DMT scavenges 88.9% of UVB-induced ROS in HaCaT cells; 100 \u03bcg\/mL reduces neutrophil ROS generation by 72%.
6. Skin barrier repair test: After 4 days of application with 2% DMT, TEWL decreases, water retention capacity improves by 1.5 times, and ceramide level in stratum corneum rises by 89%.<\/p>\n","protected":false},"excerpt":{"rendered":"

Herbal blend anti-acne and anti-mite raw material; multiple benefits: mite killing, bacteriostasis, oil control, anti-inflammation, antioxidant activity and barrier repair; acid-free formulation, improves multiple acne triggers including excessive proliferation of mites and bacteria, excess sebum and inflammatory damage<\/p>\n","protected":false},"featured_media":411,"menu_order":0,"template":"","meta":[],"product_cat":[125],"product_tag":[],"class_list":["post-228","product","type-product","status-publish","has-post-thumbnail","hentry","product_cat-kongyou-qudou-en"],"_links":{"self":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product\/228","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/media\/411"}],"wp:attachment":[{"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/media?parent=228"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=228"},{"taxonomy":"product_tag","embeddable":true,"href":"http:\/\/duanmu.9ykeji.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=228"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}