Saffron PRO
Saffron PRO
Botanical sensitive-skin repairing raw material; acts through three dimensions: skin barrier, sensory receptors and inflammatory factors; multiple benefits including barrier repair, TRPV1 channel antagonism, anti-inflammation & redness reduction, and photodamage resistance
Product overview
Saffron is known as "Plant Gold" owing to its rarity. The selected saffron originates from Iran along the ancient Silk Road. Benefiting from thousands of years of accumulated cultivation techniques and nourishment from extreme geographical conditions, it meets globally recognized quality standards with higher content of active ingredients and superior stability. It builds a natural healthy barrier from deep skin to the skin surface and revitalizes skin vitality.
Composition Information
| Component Type | INCI | CAS | EC |
|---|---|---|---|
| Components | CROCUS SATIVUS EXTRACT |
Mechanism of Action
1. Barrier repair pathway: Upregulate filaggrin expression to boost the production of natural moisturizing factors (NMF); promote fibroblast proliferation, resist UVB-induced photodamage and strengthen stratum corneum barrier.
2. Neuronal soothing pathway: Antagonize TRPV1 nociceptor, inhibit neuronal sensitization and relieve neurogenic discomfort such as stinging and burning sensation.
3. Soothing pathway: Suppress the activation of NF‑κB pathway; downregulate the release of inflammatory mediators including NO, TNF‑α, IL‑1β and IL‑6, mitigate skin inflammatory response and relieve redness.
Experimental Data
1. Filaggrin expression test: 1% Saffron PRO increases profilaggrin expression by 56% and promotes NMF synthesis.
2. UVB fibroblast protection test: 1% Saffron PRO boosts the proliferation of UVB-damaged fibroblasts by nearly 50%.
3. TRPV1 antagonism cell test: 2% Saffron PRO reverses the inhibition of cell activity induced by TRPV1 activation, restoring cell viability to 101.69%.
4. RAW264.7 cellular NO release inhibition test: 2% Saffron PRO achieves 44.8% inhibition on NO release.
5. NF‑κB pathway inhibition test: 2% Saffron PRO reduces the p‑IκB‑α/IκB‑α ratio by 72.5% compared with LPS group.
6. Inflammatory cytokine mRNA expression test: 2% Saffron PRO downregulates TNF‑α, IL‑1β and IL‑6 by 71.4%, 70.9% and 66.7% respectively.
7. Human redness test (2% Saffron PRO serum): Redness is improved after 7 days of use; facial redness fades significantly after 14 days, and the skin barrier is repaired.
Product specifications
| INCI Name: | CROCUS SATIVUS EXTRACT |
|---|---|
| Source: | The raw material is stigmas of saffron (*Crocus sativus*). It is extracted by high‑voltage pulsed electric field plant extraction technology. Its core active components include crocin, saffranal, β‑crocin and crocetin. |
| Recommended dosage: | 0.1‑1% |
| Appearance: | Pale yellow powder |
Key benefits
1. Three-dimensional synergistic repair pathway; delivers barrier repair, neural soothing and anti-inflammation to relieve redness, stinging and burning discomfort of sensitive skin.
2. Non-thermal extraction technology using high-voltage pulsed electric field; achieves instant and efficient extraction, retains active ingredients, removes impurities, with low energy consumption and no pollution.
3. Efficacy supported by multiple tests, including in vitro cell, animal and human facial redness test data.
4. Rare plant-derived raw material; saffron stigma is scarce and rich in active substances such as crocetin and crocin
Reliable B2B supply
Packaging
2 kg/drum
Storage Conditions
Sealed, cool, protected from light
Supporting Documents
- CISAR: Full Cosmetic Safety Assessment Report
- PPT: Complete Product Introduction Presentation
- FCRM: Full Raw Material Composition Report
- MFC: Manufacturing Process Flow Chart
- MSDS: Material Safety Data Sheet
- SP: Product Specification Sheet
- TDS: Technical Data Sheet
- RMI: Raw Material Information Package
